Arsenic Trioxide Concentrated Solution for Infusion (Phenasen®)

Each Phenasen vial contains arsenic trioxide 10 mg, sodium hydroxide/ hydrochloric acid for pH adjustment, and water for injections to 10 mL.

Indication:
For the induction of remission and consolidation in patients with acute promyelocytic leukaemia (APL) who are refractory to, or have relapsed from, retinoid and anthracycline chemotherapy, and whose APL is characterised by the presence of the t(15:17) translocation or PML/RAR-alpha gene expression. For the induction of remission and consolidation in patients with previously untreated acute promyelocytic leukaemia (APL) in combination with all-trans retinoic acid (ATRA) and/or chemotherapy and whose APL is characterised by the presence of the t(15:17) translocation or PML/RAR-alpha gene expression.